A case of nimesulide induced toxic epidermal necrolysis

Nimesulide-induced hepatitis and toxic epidermal necrolysis.

Ethambutol-induced toxic epidermal necrolysis.

continued. Four to fi ve days later patient again developed generalised body rashes with greater intensity for which she was referred to us. On examination she was febrile, vitals were stable, had erythematous patches over both malar prominences with haemorrhagic crusts present over the lips and anterior nares (Fig. 1), multiple areas of erosions all over the body with thick adherent yellow cru...

Phenytoin induced toxic epidermal necrolysis.

Toxic Epidermal Necrolysis (TEN) which is characterized by the detachment of the epidermis from the dermis is a rare (1.89/1.000.000 annually) and potentially life-threatening condition. The overall mortality is 20 - 30%. TEN is characterized by sudden apoptosis of keratinocytes leading to mucous membrane erosions and epidermal detachment; detachment of less than 10% of the total body surface a...

Carbamzepine-induced toxic epidermal necrolysis

Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a widespread life-threatening mucocutaneous disease where there is extensive detachment of the skin and mucous membrane. Many factors involved in the etiology of TEN including adverse drug reactions. Here we are reporting a case of toxic epidermal necrolysis in an adult male patient after receiving carbamazepine in a 38 year o...

Phenytoin-induced toxic epidermal necrolysis: a case report.

We present a case of phenytoin-induced toxic epidermal necrolysis resulting in 60-70% skin involvement. Systemic corticosteroids and prophylactic antibiotics used initially were discontinued, and subsequent management concentrated on intensive supportive treatment. The patient survived, but is left with disabling ocular complications.